Crohn s Disease ( Cd ) - 1736 Words

Crohn’s disease (CD) is a life-long, chronic, idiopathic inflammatory condition of the intestines that is characterized by frequent symptomatic relapse and remission. It involves inflammation and ulceration of various regions of the gastrointestinal tract (GI tract) lining, which often extends deep into the layers of the affected areas. The associated inflammation and ulceration of the disease affects various segments of the intestines with unaffected bowel occuring between the diseased areas. CD can involve any area of the GI tract, ranging from the mouth to the anus. However, it frequently affects the jejunum, terminal ileum (regional enteritis), and proximal colon (granulomatous colitis) (Schub, 2016). The internal presentation of CD include granulomas, which are mucosal ulcerations and nodular submucosal thickenings, that form a cobblestone appearance of the intestinal wall and leads to decreased nutrient absorption. The interference of absorption usually causes growth retardation, late puberty in children, and interferes with the quality of life. The disease may consist of abscesses, fissures, strictures, and/or thickening of the intestinal wall, which can lead to bowel obstruction. Additionally, fistulas can develop and penetrate extraintestinal structures involving the bladder, rectum, skin, and vagina (Sommers Fannin, 2015). Case Study A 17-year old female presents to the office with a history of abdominal pain, distension, and diarrhea for the last ten days. SheShow MoreRelatedThe Inflammatory Bowel Disorder Known As Crohn s Disease ( Cd )1291 Words   |  6 Pagespaper is to apprise to the reader pivotal information on the inflammatory bowel disorder known as Crohn’s Disease (CD). It is a rare disease that is usually not wanted to be discussed by its sufferers, due to its sensitive nature of being a digestive problem. Luckily, as this paper will show, it is now an issue slowly, but surely, being explored more openly. A short introduction to the chronic disease will be divulged, pathophysiology and etiology will be discussed to prepare the reader. Works researchedRead MoreSymptoms And Treatment Of Crohn s Disease1021 Words   |  5 PagesJoan Friedlander. Crohn’s is an autoimmune disease that affects many parts of the body. These parts include, but are not limited to the eyes, skin, liver, and most heavily the intestines. When you have Crohn s disease, your body s immune system begins attacking all of healthy cells in your GI tract, which causes inflammation. Crohn’s is an incurable disease, but because of new medicine and treatment options, Crohn’s has become a livable disease. Crohn s has many different symptoms, and these symptomsRead MoreSymptoms And Treatment Of Crohn S1008 Words   |  5 PagesVULVAR CROHN`S IN A PREPUBERTAL GIRL ON INFLIXIMAB Key words Vulvar Crohn`s. Crohn`s disease. Infliximab. Pre pubertal girls. Abstract Crohn`s disease is an inflammatory bowel disease. It often manifests as chronic diarrhea, abdominal pain, weight loss and blood in the stool. It usually involves any part of the gastrointestinal tract and sometimes presents with extra intestinal manifestations like uveitis, dermatitis, arthritis and anemia. Extra intestinal findings like Vulvar lesions are lessRead MoreThe Role Of Nutrition Therapy And Crohn s Disease938 Words   |  4 PagesNutrition Therapy and Crohn’s Disease The Role of Nutrition Therapy in Crohn’s Disease According to the Crohn’s and Colitis Foundation of America, Crohn’s disease (CD) may affect as many as 780,000 Americans1. The exact time of the onset of the disease is unknown, but it often starts between the age of 15 and 35 for both men and woman. Currently, the diagnosis, etiology, treatment, and cure of CD remain undefined. However, recent research suggests that hereditary, genetics, and/or environmentalRead MoreCrohn s Disease And The Inflammatory Process1108 Words   |  5 Pages Crohn’s Disease and the Inflammatory Process Crohn s disease is an inflammatory process in the intestines that is marked by abnormal inflammation of the GI tract. Crohn’s disease is treated with a variety of single or combined therapies that work at decreasing inflammatory process. Within this essay, I will discuss the etiology and pathophysiology of Crohn’s disease, the evidence- based- practice treatment of Crohn’s and how these medications work in reducing the inflammatory process. IRead MoreThe Importance Of Nutrition On Inflammatory Bowel Disease1607 Words   |  7 Pages. Lucendo, A. J., De Rezende, L. C. Importance of nutrition in inflammatory bowel disease. World Jour of GastroenteroL. 2009. WJG, 15(17), 2081–2088. http://doi.org/10.3748/wjg.15.2081’ This peer review article highlights the fundamental role that nutrition therapy plays in the clinical management of all patients with CD. The review concentrates specially in correcting macro and micronutrient deficiencies in frequently malnourished patients, focusing on reversing the physiopathological consequencesRead MoreEvaluation And Treatment Of Fistulas952 Words   |  4 Pagesimportant to determine the origin or source of the fistula. It can originate from oesophagus, stomach, small bowel, large bowel or even bladder or other organs of the body. Some fistulas can complicate healing in post-surgical wounds and in chronic disease. Depending of the origin, the leaking fluid will change in composition. Also, it may be important to classify the amount of drainage from the fistula as low output ( 200 mL/ 24h) or high output ( 200 mL/ 24h). Then, it is important to assessRead MoreHow Mongersen Is Increase Anti Inflammatory Cell Signaling Essay1735 Words   |  7 Pages -1. Sketch how mongersen is expected to increases anti-inflammatory cell signaling. (10%) Since gut inflammation of Crohn’s disease is characterized by abnormal decreases in the activity of the immunosuppressive cytokine transforming growth factor (TGF)–Î ²1, which is induced by the increased level of SMAD7 protein, because it would prevent TGF-ÃŽ ²1–associated and SMAD-associated signaling.[1] The formulation of Mongersen (formerly GED-0301) contains a 21-base single-strand phosphorothioate oligonucleotideRead MoreSymptoms And Symptoms Of Inflammatory Bowel Disease ( Ibd )1316 Words   |  6 Pagescauses and diseases related to these symptoms. It was awkward and unpleasant to deal with the symptoms for him. He felt weak and started to lose weight. Eventually, Mr. A was diagnosed with crohn’s disease (CD) a type of inflammatory bowel disease (IBD) in 2012. IBD is a collective group of disorders that are chronic and incurable and characterised by inflammation in the intestinal tract. (Chang Johnson, 2014, p.446). Crohn’s disease (CD) a nd ulcerative colitis (UC) are autoimmune diseases, where theRead More Inflammatory Bowel Disease Essay1452 Words   |  6 PagesThe term Inflammatory Bowel Disease (IBD) is a general name given to a few disorders that all fall under the category of inflamed intestines (they become red and swollen.) This is usually due to a reaction the body causes against its own intestinal tissue. The two most common types of Inflammatory Bowel Disease are Ulcerative Colitis (UC) and Crohn’s Disease (CD). Crohn’s disease can affect any part of the gastrointestinal tract; however, it more commonly affects the small intestine or colon. Inflammatory